Project Description

Hydroxyapatite Microspheres

Medical grade Hydroxyapatite/HA micorpsheres are spherical HA microbeads which are mostly used as thermal spray coatings on orthopedic devices, 3D bio priting. Our 25-45um HAP microspheres can also be used in medical aesthetics as raw material of HA dermal fillers, which is a clone to Radiesse.

  • EPRUI supplies medical grade HA microspheres which meet Chinese standard YY0303-1998 and International Standard ASTM F 1185-2003

  • Excellent Biocompatibility
  • Used as thermal spray coatings on orthopedic devices
  • 25-45um HAP microspheres, a clone to HA microbeads used in Radiesse
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  • Hydroxyapatite Microspheres
  • 25-45um Hydroxyapatite Microspheres
  • HAP powder for thermal spraying

EPRUI Biotech Trusted By

  • Harvard University
  • Agilent Technologies
  • ChemGenes Corporation
  • SamSung
  • Stanford University
  • Massachusetts Institute of Technology
  • illumina
  • UC Berkeley
  • Tsinghua University
  • Fudan University
  • Tongji University
  • KAUST
  • Imperial College London
  • Korea University
  • National University of Singapore
  • University of Minnesota
  • Vanderbilt University
  • Washington University

EPRUI HAP Microspheres Specifications

TypeItem No.MorphologyParticle SizePurityApplication
EPRUI-0707-15uSpherical15um(≤30um)99%3D bioprinting, thermal spray coatings on orthopedic devices, which can replace similar products from Bio-rad.
EPRUI-0707-25-45uSpherical25-45um99%HAP Dermal fillers, which is a clone to Radiesse.
EPRUI-0707-50uSpherical50um(30-80um)99%3D bioprinting, thermal spray coatings on orthopedic devices, which can replace similar products from Bio-rad.
EPRUI-0707-100uSpherical100um(≥80um)99%3D bioprinting, thermal spray coatings on orthopedic devices, which can replace similar products from Bio-rad.
EPRUI-0707-200uSpherical200um99%3D bioprinting, thermal spray coatings on orthopedic devices, which can replace similar products from Bio-rad.
EPRUI-0707-3hSpherical3mm99%Bone filling materials, bone void filler,

Why Choose EPRUI Biotech

Excellent Quality

· Precise particle size
· Narrow particle size distribution
· Perfect spherical morphology
· Optimized pore size

Competitive Price

Based on the same or even better quality, we offer much more competitive price than domestic and overseas rivals.

Customization Service

EPRUI offers customization service for special requirement of particle size. E.x. EPRUI once customizes 120-210um highly crosslinked PS/DVB microspheres for a Taiwan customer

Free Delivery

If order above USD$1000, we offer free delivery service.

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Buying Guide of Medical Grade HA Microspheres

1. Molecular Structure of Hydroxyapatite Microspheres

Hydroxyapatite Microspheres Molecular Structure

2. EPRUI HAP Microspheres Specifications

Chemical nameHydroxyapatite microspheres, HAP/HA microbeads
AppearanceWhite powder
MorphologySpherical
Diameter10-200μm
GradeMedical Grade
StandardYY/T 0683-2008; ASTM F 1185-2003
Molecular Weight1004
Formula Ca10(PO4)6(OH)2
Cas No.1306-06-5
Density3.16g/cm3
Melting Point1650 ℃

3. What are applications of medical HAP microspheres?

  • 3D bioprinting material
  • Medical implant materials such as hydroxyapatite bioceramics as well as thermal spray coating for medical implants.
  • Artificial bone repair scaffold material
  • Dermal fillers

4. What are the synthesis methods for HAP microspheres?

The raw material of our calcium phosphate is produced by solid-phase method or liquid-phase method according to different uses.

The large HAP particles are made spherical through granulation process (the granulation process is a technology to make out spherical morphology), and then the sintering process is performed.

At last, sieving the HA microspheres in order to achieve the ideal particle size range. Besides, we use spray drying method to get spherical HA microspheres with small particle size.

5. What are advantages of spherical HA/HAP?

Hydroxyapatite (Ca10 (PO4) 6 (OH)2), abbreviated as HA or HAP, has similar chemical composition and structure to the bone tissue of living organisms. It has good biocompatibility and biological activity.

HA microspheres with spherical morphology have high packing density and uniform stress distribution, which can increase the powder fluidity and can reduce the intensity, which makes the biocoating more smooth.

6. Why choose HA microspheres from EPRUI?

  • EPRUI supplies HAP microspheres which meet Chinese pharmaceutical standards YY / T 0683-2008 which is corresponding to International Standard ASTM F 1185-2003
  • We can supply 25-45um HAP microspheres with 100% sterilized by irradiation. Therefore, our HAP microspheres are ready to be injected or implanted into human body
  • The lab to make medical grade HA and TCP biological materials is built according to GMP requirement.
  • EPRUI uses the method of simulating body fluid to produce medical use HA whiskers, which makes the product more biocompatible.
  • EPRUI provides customization service and professional technical support for your research products.

7. How to order

Please send e-mail to: sales@epruibiotech.com or call us by 86-21-64192663 for products inquires.

For detailed steps, please visit: How to Buy

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